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Olson: Clinical Pharmacology Made Ridiculously Simple (Edition 3), by James Olson
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Provides general principles of pharmacology. Includes tables to compare different agents within a given class of drugs. For use as a review for Boards, self-testing, or reference. Previous edition: c1997.
- Sales Rank: #1341691 in Books
- Brand: Brand: MedMaster Inc.
- Published on: 2006-02-01
- Released on: 2006-02-01
- Original language: English
- Number of items: 1
- Dimensions: .50" h x 8.40" w x 10.70" l, 1.20 pounds
- Binding: Paperback
- 162 pages
- PClincal Pharmacology Made Ridculously Sinple, Author James Olson, M.D., Edition 3,Coprig ht 2006, Paperback,
- Pages 163
About the Author
Associate in Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington; Instructor in Pediatrics, Univ of Washington/Children's Hospital and Medical Center, Seattle, Washington.
Most helpful customer reviews
6 of 6 people found the following review helpful.
Great for review, bad for learning
By Cliff W. Arceneaux
While in school, I enjoyed the pictures and such. But found the book tough to learn from. Maybe I don't handle gigantic lists that well.
Now that I'm out practicing, I like the book alot as a quick reference/refresher.
2 of 2 people found the following review helpful.
Great book for covering the basics!
By Mary Marston St John
This is a wonderful book for those who are interested in the basics of pharmacology. Every chapter covers a different aspect of the body and the effects that pharmaceuticals have on it. Covering difficult concepts about the central, peripheral and autonomic nervous systems, the book utilizes charts and "cute" animations to illustrate how certain drugs act on specific receptors. In a sense this book could be considered to be a version of Cliff's Notes for pharmacology students.
However, while the book is straightforward and correct about the actions of the categories of drugs (for example, beta blockers), there are several errors in the pharmaceutical charts regarding the specific actions and side effects of certain medcines. Please check with your professors or a more knowledgable authority concerning these errors.
4 of 7 people found the following review helpful.
Not very helpful.
By Justin Hamlin
I'm not sure how this book ended up in the Ridiculously Simple series. Maybe because of brevity with the subject? It reads like an abbreviated text. It does put some abbreviated information in table form, but it's overly complicated and doesn't streamline the information any better than a typical, bloviating text book does. Not interesting. Few helpful pointers. Just the same information presented in a slightly different way. Well, almost the same. It actually gets quite a few things wrong. For instance, it states that D1 and D2 receptors are both inhibitory. It even places emphasis on this in the text with Italics. In fact, D1 receptors are excitatory, but D2 receptors are inhibitory. This is CRITICAL to know in order to understand movement disorders such as Parkinsonism so you can know how the drugs work. Another example, it indicates that the half life for fluoxetine is 48 - 72 hours. While technically correct, the pharmacokinetics appear to be nonlinear resulting in a longer half life with more than one dose, which is how a patient is going to take it. Further, its first metabolite is norfluoxetine, which is similarly as potent as fluoxetine, but has a longer half life. They don't present this critical information in this book. Another incorrect statement: They claim that drug tolerance to psychoactive substances such as alcohol is due to cytochrome P450 inactivation. This is not correct. While cytochrome P450 is the most important factor in the liver's metabolizing of many substances, tolerance is actually a purely psychological factor. Studies have shown that tolerance occurs when drug use occurs in the same surroundings repeatedly. If a person who has tolerance to the drug is moved to unfamiliar surroundings, all tolerance to the substance is gone. With abuse, and increasing use of a substance, of course cytochrome P450 will build up to handle the increased load, but simply having an understanding of Michaelis-Menten kinetics shows that there is a maximum rate that will be achieved, and the deactivation rate of compounds will not proceed any further based on just increasing the enzyme to match the substrate concentration increases. Therefore, although the person can consume more of the substance, this doesn't mean that they have a tolerance. They get just as intoxicated, they just don't overdose as easily.
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